| Equipment Leica SP5 confocal Leica SP8 confocal Zeiss 510 inverted confocal Zeiss 510 upright confocal Zeiss 710 confocal Zeiss 780 upright confocal Zeiss 780 inverted confocal Olympus multiphoton Spinning disk TIRF DeltaVision Live cell station Live cell station 2 VivaView Axio Observer Axio Imager Leica DMI 4000 Lumar stereoscope Dissecting scope Laser capture Lifetime Gizmos Workstations Capabilities Services New Users Booking Rules Fees Image analysis Data server Guides and courses Sample preparation Reference links News and events About LMCF Personnel Location Contacts Publications Image gallery Feedback Ask a question Report a problem Search |
About LMCF The Light Microscopy Core Facility (LMCF) offers a wide range of confocal and conventional fluorescence microscopes and image analysis resources. The facility is based in the LSRC, the FFSC (French Family Science Center), the Nanaline Duke building and Research Park II at Duke University and is open to all members of the University and the Medical Center campuses. As a centrally funded shared resource, we aim to offer affordable and efficient access to standard and advanced imaging instrumentation for users of all levels of experience and from any discipline. Dedicated staff provide training and full technical support for all the instruments. If you are interested in using imaging techniques in your research, please see the equipment, capabilities, courses, guides and services offered by the facility and request training for any resource you wish to use. If you have any questions, please contact the facility.
The facility recovers some of the direct costs through user fees. The fees for using the microscopes are heavily subsidized by generous funding from the following sources: Shared instrumentation grant 1S10RR027528-01 funded the DeltaVision, shared instrumentation grant 1S10RR027867-01 funded the intravital confocal/multiphoton systems, IDG #2011-IDG-1002 from NCBC funded the Olympus VivaView. Use The facility is heavily used by many labs from across Duke. Since begining operation LMCF has been used over 42,000 times by over 1200 users from over 320 labs across all research departments totaling over 110,000 hours of use. Many publications have resulted from the use of the microscopy facility in recent years. Images from the microscopes can be seen in the image gallery. History LMCF was
initially formed from several departmental microscope resources
in the LSRC. The Department of Biology and the Department of
Pharmacology & Cancer
Biology teamed up, along with the then Comprehensive Cancer Center's
Confocal Microscopy Shared Resource, to hire a Director
in 2006 to establish and
run a cooperative microscope facility for the two departments. The facility is overseen by a Faculty Advisory Committee, which in turn is overseen by designates of the Provost and the Dean of the Medical School. Oversight Committee Sally
Kornbluth (Vice Dean for the Basic Sciences) LMCF in the news Inside Duke Article from July 2007 | DukeMed Magazine article from Winter 2008 | Duke Research image March 2008 | Duke Research image Jan 2009 | Cancer Center Newsletter March 2009| News and Observer article October 2010 | Duke Today Spotlight 2013 About microscopy.duke.edu The LMCF website aims to be a clear and concise source of relevant information. If you spot any mistakes or have comments or suggestions for improvements please let us know.
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